The global trade framework in the context of WTO is getting weaker, thus the United States has been actively promoting Trans-Pacific Partnership Agreement (TPP). After Japan joined 12 of the TPP negotiation members, it accounts nearly 40% of the global GDP and about 1/3 of the world trade. Remarkably, China as the world's second largest economy is excluded from the TPP. So, how should China deal or respond to TPP? How much will it cost for China to join TPP? What are China's strategic options?